Dr. Allison Abbott was
invited to be a featured speaker at The MicroRNA Revolution: The 2012 Dr. Paul
Janssen Award Symposium, this September in New York City. This symposium honored
Drs. Victor Ambros and Gary Ruvkun who identified and characterized the first
microRNA. Dr. Ambros' laboratory yielded the discovery of the first microRNA and
Dr. Ruvkun's laboratory identified how that microRNA regulates its target
messenger. Together, they demonstrated that the microRNA inactivates its target
through direct, base-pairing interactions. Since their discovery, the small RNA
field has grown to thousands of papers, many focused on particular diseases and
potential treatments. Dr. Abbott, who worked in Dr. Ambros' lab as a post-doctoral fellow,
discussed genetic approaches used to identify pathways and targets regulated by
microRNAs in animal development.