John F. LaDisa, Jr., Ph.D.
Associate Professor of Biomedical Engineering
Office: Engineering Hall, 311
E-mail: john.ladisa@marquette.edu
Research interests
- Quantify hemodynamic and physiologic alterations as indices of morbidity after surgical or transcatheter treatments for congenital diseases
- Characterize interactions between altered hemodynamics associated with stent implantation, diabetes or atherogenesis and the development of neointimal hyperplasia
- Design and implement novel engineering devices and interventions for the treatment of cardiovascular diseases, particularly in children
- Develop tools for predictive surgical or interventional treatment planning
Professional preparation
Postdoctoral Scholar, 2004-06, Pediatric Cardiology, Stanford University
Ph.D., 2004, Biomedical Engineering, Marquette University
M.S., 2001, Biomedical Engineering, Marquette University
B.S., 2000, Biomedical Engineering, Marquette University
Selected recent publications
Timothy J. Gundert, Andrew R. Williams, Bon-Kwon Koo, Jeffrey A. Feinstein, John F. LaDisa, Jr. A rapid and computationally inexpensive method for assessing patient-specific hemodynamic alterations introduced by commercially available and next-generation stents. To be submitted to Annals of Biomedical Engineering, Nov. 20, 2009.
Andrew R. Williams, Bon-Kwon Koo, Timothy J. Gundert, Peter J. Fitzgerald, John F. LaDisa, Jr. Local hemodynamic changes caused by main branch stent implantation and subsequent side branch balloon angioplasty in a representative coronary bifurcation. Submitted to JACC: Cardiovascular Interventions, Oct. 26, 2009.
John F. LaDisa, Jr., Mark R. Bowers, Leanne Harmann, Robert Prost, Anil Doppalapudi, Tayyab Mohyuddin, Osama Zaidat, Raymond Q. Migrino. Time-efficient patient-specific quantification of regional carotid artery fluid dynamics and spatial correlation with plaque burden following statin treatment. Tentatively accepted to Medical Physics, Sept. 2, 2009.
H. J. Kim, I. E. Vignon-Clementel, C. A. Figueroa, John F. LaDisa, Jr., K. E. Jansen, J. A. Feinstein and C. A. Taylor. On coupling a lumped parameter heart model and a three-dimensional finite element aorta model. Ann Biomed Eng. 2009 Nov; 37(11):2153-69.
John F. LaDisa, Jr., Lars E. Olson, Douglas A. Hettrick, David C. Warltier, Judy R. Kersten, and Paul S. Pagel. Alterations in regional vascular geometry produced by theoretical stent implantation influence distributions of wall shear stress: analysis of a curved coronary artery using 3D computational fluid dynamics modeling. Biomed Eng Online. 2006 June 16; 5:40.
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