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Biomedical Engineering Courses
Undergraduate Courses in Biomedical Engineering
BIEN 1. Introduction to Biomedical Engineering Methods 1 2 sem. hrs.
Introduction to biomedical engineering design and problem solving using computers. Key elements include flow-charting, statistics, graphics, measurement and error, teamwork and decision- making. Problem-solving elements will be applied to real-world biomedical problems introduced by practicing biomedical engineers as well as faculty. Programming assignments will use existing software packages as well as a high level programming language.
BIEN 2. Introduction to BiomedicalEngineering Methods 2 2 sem. hrs.
Continuation of BIEN 1 professional Biomedical Engineer presentations and more advanced software applications and programming methods. Prereq: BIEN 1.
BIEN 84. Statistics for Biomedical Engineering 1 sem. hr.
Numerical and graphical summary of biomedical data and the use of statistics in problem solving for a variety of case studies in biomedical research, medical device design and clinical trials. Prereq: MATH 80.
BIEN 91, 93, 95, 97. Co-op Work Period 1, 2, 3, 4. 0 sem. hrs.
Registration for approved cooperative education program work assignments is required of all coop students. Grading and credits are accomplished in the accompanying following term when registered for courses numbered 92, 94, etc. Fee.
BIEN 92, 94, 96, 98. Co-op Grading Period 1, 2, 3,4. 1 sem. hr.
Grading for preceding co-op work assignments is accomplished by review of Employer Evaluation Forms, Work Exit Reports, and other materials as required during each term in school following a work period. A nominal fee is charged for registration for Work Periods. No tuition is charged for Grading Periods. S/U grade assessment.
BIEN 100. Biomedical Circuits and Electronics 4 sem. hrs.
An experience in electrical circuits (AC and DC), electronic devices (Junction, Transistor, Operational, Amplifier) bridges, digital circuits and Boolean implementation, combinational and sequential logic, memories. Use of P-Spice software. Analysis and design. Prereq: MATH 83 and PHYS 4; or MATH 87 and PHYS 4.
#BIEN 112. Embedded Biomedical Instrumentation 3 sem. hrs.
Fundamentals of digital circuit design and analysis and the application to embedded biomedical instrumentation. Topics include microprocessor principles and programming and system design contraints for medical electronics. Laboratory will provide applications of concepts introduced in class. Offered spring term. Prereq: BIEN 100.
BIEN 146. Principles of Design 3 sem. hrs.
Course content focuses on a structured product design and development process that includes project definition, customer needs identification, product specification, concept generation, and concept selection. Course also focuses on issues related to teamwork, project management, and effective communication. Student team design projects culminate in the development of a technically and economically viable concept and a proposal for future development of this concept (done in the second semester of this two-course sequence). Offered fall term. 2 hrs. lec., 2 hrs. lab. Prereq: Sr. stndg.; co-op students, jr. stndg.
BIEN 147. Senior Design Project 3 sem. hrs.
Course focuses on detailed design, prototyping, and testing design concepts. Course includes topics directly relevant to student design projects and careers in the engineering profession. Student team design projects culminate in a final report that documents the performance and details (engineering drawings and/or documentation) of their final design. Offered Spring semester. 2 hrs. lec., 2 hrs. lab. Prereq: BIEN 146.
#BIEN 151. Topics in Biomedical Engineering 1-3 sem. hrs.
Course content announced prior to each term. Students may enroll in the course more than once because subject matter changes. Possible topics include biomechanics, experimental methods, neuroanatomy, telemetry, etc. Offered occasionally. Prereq: Jr. stndg.
#BIEN 152. Analysis of Physiological Models 3 sem. hrs.
Development of continuous (compartmental), and distributed-in-space-and-time mathematical models of physiological systems and molecular events. Analytical and numerical methods for solving differential equations of the initial and boundary value types. Simulation of model response, and estimation of model parameters using linear and nonlinear regression analysis. Prereq: Jr. stndg. and MATH 83; or jr. stndg. and MATH 87.
#BIEN 153. Applied Finite Element Analysis in Biomechanics 3 sem. hrs.
This course will introduce the finite element solution method for linear, static problems. The course will include calculation of element stiffness matrices, assembly of global stiffness matrices, exposure to various finite element solution methods, and numerical integration. Although the course will emphasize structural mechanics, heat transfer and fluid mechanics applications in finite element analysis also will be discussed. Computer assignments will include development of finite element code (FORTRAN or C) and also use of commercial finite element software (ANSYS and/or MARC). Prereq: Sr. stndg., BIEN 2, and ENME 130; or Sr. stndg., ENME 130, and GEEN 40.
BIEN 155. Signals and Systems for Biomedical Engineering 4 sem. hrs.
Mathematical models of continuous-time signals and systems are studied in this course. The time domain viewpoint is developed for linear time invariant systems using the impulse response and convolution integral. The frequency domain viewpoint is also explored through the Fourier Series and Fourier Transform. Basic filtering concepts including simple design problems are covered. Application of the Laplace transform to block diagrams, linear feedback, and stability including Bode plots are discussed. The sampling theorem, the Z-Transform, and the Discrete Fourier Transform are introduced. Examples of electrical, mechanical, and biomedical signals and systems are used extensively throughout the course. Offered both terms. Prereq: EECE 12 with minimum grade of C and MATH 83; or BIEN 100 with minimum grade of C and MATH 83; or EECE 12 with minimum grade of C and MATH 87; or BIEN 100 with minimum grade of C and MATH 87.
#BIEN 157. Intelligent Biosystems 3 sem. hrs.
Principles and performance of physiological control systems with emphasis on the use of simulation as a tool to understand normal and pathological dynamic mechanisms. Models of human technology biosystems targeting the interface and clinical decision-support systems. Survey of intelligent systems tools (adaptiveneural networks, fuzzy systems, genetic algorithms) for smart biomonitoring and approximating biocontrol systems. Prereq: BIEN 155 or cons. of instr.
#BIEN 160. Neural Engineering 3 sem. hrs.
Basic principles of neural engineering, properties of excitable tissues, quantitative models used to examine the mechanisms of natural and artificial stimulation. Basic concepts for the design of neuroprosthetic devices for sensory, motor and therapeutic applications. Design issues including electrode type, biomaterials, tissue response to stimulating electrodes and stimulus parameters for electrical stimulation and artificial control. Examples of how engineering interfaces with neural tissue show increasing promise in the rehabilitation of individuals of neural impairment. Prereq: MATH 83 and PHYS 4; or MATH 87 and PHYS 4.
#BIEN 167. Rehabilitation Engineering: Telerehabilitation Research Tools 3 sem. hrs.
Focuses on innovative research tools that can be used for remote assessment and rehabilitative therapy. Topics include an overview of sensorimotor systems that are critical for interactive communication and control, healing processes for functional impairments due to neuromusculoskeletal and cardiopulmonary pathology, tools for human performance and outcomes assessment, videoconferencing and wireless technologies, augmentative communication tools, tools for ergonomic and product usability analysis, accessibility considerations for human-technology interfaces, principles of universal design, and roles for context-aware intelligent systems. Each student will be involved in a team project that develops and evaluates a research protocol utilizing telerehabilitation tools. Prereq: BIEN 100 or equiv.
#BIEN 168. Rehabilitation Engineering: Prosthetics, Orthotics, Seating and Positioning 3 sem. hrs.
This course will present an overview of biomedical engineering as it applies to Rehabilitation Engineering, specifically, the design and prescription of prosthetic limbs, orthotic devices, and seating and positioning systems. Topics to be covered include: medical terminology, musculoskeletal anatomy, muscle mechanics, soft tissue mechanics, gait/locomotion, amputation surgery, lower extremity prosthetics, lower extremity orthotics, hand function, electromyography, upper extremity prosthetics, upper extremity orthotics, seating and positioning, and assistive devices. Prereq: ENME 20 or ENME 22.
#BIEN 170. Introduction to Biomaterials Science and Engineering 3 sem. hrs.
This course is designed to introduce the uses of materials in the human body for the purposes of healing, correcting deformities, and restoring lost function. The science aspect of the course encompasses topics including characterization of material properties, biocompatibility, and past and current uses of materials for novel devices that are both biocompatible and functional for the life of the implanted device. Projects will allow students to focus and gain knowledge in an area of biomaterials engineering that they are interested in. Prereq: MEEN 60 or cons. of instr.
#BIEN 172. Biotechnology Instrumentation 3 sem. hrs.
The presentation of biotechnology instrumentation will be based on the application of the following topics: boundary value problems (modeling of one and two dimensional distributions of temperature and electric fields); optics (sources, filters, cells, and sensors); control of electric fields; heat transfer and temperature control; motor control for mechanical and fluid movements. The molecular biology and engineering principles will be presented for each type of instrument or process. Students will be expected to analyze and evaluate commercially available systems, and propose design improvements.
#BIEN 175. Structure-Property Relationship of Biological Materials 3 sem. hrs.
This course is designed to critically review the structure-property relationships of biological materials. Structure-property relationships for skin, bone, ligaments, tendons, muscle, and organs will be discussed. The effect of pathology, state of the tissue, and age on material properties of tissues and organs will be discussed. This course also critically reviews the testing methods used to obtain mechanical behavior of the biological tissues and organs.
#BIEN 180. Systems Physiology 3 sem. hrs.
Analyses of the underlying physiologic and bioengineering aspects of the major cell and organ systems of the human from an engineer’s point of view. Classic physiologic approaches used to introduce topics including cell functions, nervous system, nerve, muscle, heart, circulation, respiratory system, kidney, reproduction and biomechanics. Design problems including models of cell-organ-system function and problems in biomechanics illuminate topics covered. Computer techniques and relevant instrumentation are incorporated. Experts on related topics are invited to speak as they are available. Prereq: Jr. stndg.
#BIEN 182. Medical Imaging Physics 3 sem. hrs.
Students learn how light, x-rays, radiopharmaceuticals, ultrasound, magnetic fields, and other energy probes are generated and how they interact with tissues and detectors to produce useful image contrast. Practical issues such as beam generation, dose limitations, patient motion, spatial resolution and dynamic range limitations, and cost-effectiveness will be addressed. Emphasis is placed upon diagnostic radiological imaging physics, including the planar x-ray, digital subtraction angiography mammography, computed tomography, nuclear medicine, ultrasound, and magnetic resonance imaging modalities. Prereq: Jr. stndg. And PHYS 4; or Jr. stndg. and cons. of instr.
#BIEN 183. Cardiopulmonary Mechanics 3 sem. hrs.
Examination of the physiological behavior of the cardiovascular and pulmonary systems from an engineering perspective. Emphasis is on understanding the mechanical basis of physiologic phenomena via experimental models. Prereq: BIEN 180, which must be taken concurrently, or equiv.; and BIEN 186, which must be taken concurrently, or equiv.; or cons. of instr.
#BIEN 184. Image Processing for the Biomedical Sciences 3 sem. hrs.
This course serves as an introduction to biomedical image processing. Topics explored included the human visual system, spatial sampling and digitization, image transforms, spatial filtering, Fourier analysis, image enhancement and restoration, nonlinear and adaptive filters, color image processing, geometrical operations and morphological filtering, image coding and compression image segmentation, feature extraction and object classification. Applications in diagnostic medicine, biology and biomedical research are emphasized and presented as illustrative examples. Prereq: MATH 80 and MATH 81; knowledge of C programming; or cons. of instr.
BIEN 185. Computer Applications in Biomedical Engineering 3 sem. hrs.
Design and implementation of personal computer (PC) techniques for data acquisition and analysis in the Biomedical laboratory and clinical environments. Emphasis on data acquisition and algorithm design using the C language. Real time processing of analog signals accomplished during assigned projects on PC workstations. Prereq: BIEN 2, GEEN 21,or GEEN 40.
BIEN 186. Transport Phenomena for Biomedical Engineers 3 sem. hrs.
Applications of mass, momentum, and mechanical energy balances to biomedical fluid systems. Study of physiological phenomena with an emphasis on cardiovascular systems and blood rheology. Prereq: ENME 22, ENME 20, or cons. of instr.
#BIEN 187. Biomedical Instrumentation Design 3 sem. hrs.
Problems in instrumentation relating to physiological measurements in the laboratory and clinic. Electronic devices for stimulus as well as measurement of physiological quantities. Design of actual instruments. Features include mechanical design, accessory design and safety requirements. Prereq: BIEN 100 and BIEN 155; or EECE 111 and EECE 113.
BIEN 188. Bioelectronics Design Lab 1 3 sem. hrs.
The use of medical instruments in the hospital environment. Understanding the principles of operation, safe operating procedures and methods of instrument selection. Design of experiments to measure physiological parameters. Actual medical instruments used under approximate clinical conditions. Report writing. 2 hrs. lec., 3 hrs. lab. Prereq: EECE 41, EECE 42, EECE 111.
BIEN 189. Bioelectronics Design Lab 2 3 sem. hrs.
Design of circuits used in research and clinical instrumentation. Experiments include the design, fabrication and evaluation of specific circuits. Typical projects include circuits used for: patient isolation from electrical hazard, measurement of heart rate, multiplexing and demultiplexing and analog to digital conversion. Design projects incorporating microprocessors are also included. students required to submit reports. 2 hrs. lec., 3 hrs. lab. Prereq: BIEN 188 and EECE 143.
BIEN 191. Biomechanics Design Lab 1 3 sem. hrs.
Intended for those students pursuing the Biomedical Engineering Biomechanics option. The application of principles of engineering mechanics, data acquisition and basic electronics in the design and utilization of biomechanical instrumentation. Principles of transduction, mechanics, sampling theory, strain, temperature, and flow measurement as applied to biomechanical systems. A background in data acquisition, electrical safety, operational amplifier and bridge circuits, and measurements is provided. Experiments investigate biomechanics of the musculoskeletal and cardiovascular systems and include design content. Report writing. 2 hrs. lec., 3 hrs. lab. Prereq: BIEN 100, ENME 20, and ENME 130.
BIEN 192. Biomechanics Design Laboratory 2 3 sem. hrs.
The Biomechanics Design Laboratory provides students with experience in the design and implementation of appropriate experimental procedures to analyze biomechanical problems. Students will become familiar with various types of advanced transducers which will be used in conjunction with data acquisition workstations to obtain thermal, flow, strain, and related physiological data from biomechanical systems. Topics include mechanical properties of active muscle; analysis of human motion; postural stability; thermal regulation; cardiovascular mechanics; stress distribution in skeletal system; and comparison of static and dynamic biomechanical responses to load. 2 hrs. lec., 3 hrs. lab. Prereq: BIEN 191.
BIEN 193. Biocomputers Design Lab 1 3 sem. hrs.
Hands-on experience in software design and validation, microprocessors, computer architecture, real-time computing, embedded software, graphical user interface and networking. An emphasis on medical devices with embedded software and hardware. Offered fall term. Prereq: BIEN 100, BIEN 112, BIEN 155, and BIEN 185.
BIEN 194. Biocomputers Design Lab 2 3 sem. hrs.
Continuation of BIEN 193 with emphasis on high performance computing in workstation environments. Offered spring term. Prereq: BIEN 193.
BIEN 195. Independent Study 1-4 sem. hrs.
Undergraduate independent study project of either a theoretical or experimental nature. Offered every term. Prereq: Jr. stndg., 3.000 Q.P.A ., cons. of instr., and cons. of dept. ch.; or sr. stndg., 3.000 G.P.A., cons. of instr., and cons. of dept. ch.
List of Undergraduate Courses that may carry Graduate Credit
***Descriptions can be found above***
BIEN 112. Embedded Biomedical Instumentation
BIEN 151. Topics in Biomedical Engineering
BIEN 152. Analysis of Physiological Models
BIEN 153. Applied Finite Element Analysis in Biomechanics
BIEN 157. Intelligent Biosystems
BIEN 160. Neural Engineering
BIEN 167. Rehabilitation Engineering: Telerehabilitation Research Tools
BIEN 168. Rehabilitation Engineering: Prosthetics, Orthotics, Seating and Positioning
BIEN 170. Introduction to Biomaterials Science and Engineering
BIEN 172. Biotechnology Instrumentation BIEN 175. Structure-Property Relationship
of Biological Materials
BIEN 180. Systems Physiology
BIEN 182. Medical Imaging Physics
BIEN 183. Cardiopulmonary Mechanics
BIEN 184. Image Processing for the Biomedical Sciences
BIEN 187. Biomedical Instrumentation Design
Graduate Courses in Biomedical Engineering
BIEN 201. Analysis of Physiological Systems 3 sem. hrs.
Introduction to the use of mathematical models in quantifying physiological systems. Model formulation will be analyzed. Applications of analytical and numerical solution techniques and parameter estimation methods. Offered occasionally. Prereq: BIEN 152.
BIEN 202. Bioelectric Phenomena 3 sem. hrs.
Electrophysiology of excitable membranes, electromagnetic fields in volume conductors, mathematical models of neural elements and volume conductor fields. Offered occasionally.
BIEN 205. Cellular and Molecular Bioengineering 3 sem. hrs.
Main topics include: cellular biomechanics with an emphasis on the cardiovascular system, molecular bioengineering, biotransport phenomena, and tissue engineering with focus on artificial internal organs. Cellular biomechanics topics covered are biomechanics of the endothelium, endothelial-immune cell interactions, and blood cell structural biomechanics. Topics in molecular bioengineering include chemotaxis and chemokinesis, and modeling of receptor-mediated endocytosis. Biotransport and tissue engineering topics include bioreactor design and the analysis and development of artificial internal organs like the liver and pancreas. Offered occasionally.
BIEN 210. Biofluid Mechanics 3 sem. hrs.
Development of the theory of fluid mechanics as applied to living systems. Both steady and unsteady flows of Newtonian and non-Newtonian fluids will be considered. Topics to be covered include viscometry, blood flow, gas and aerosolflows, pulsatile flow and wave propagation and applications to the understanding of flows in organs and to the measurement of blood pressure and flow. Offered alternate years. Prereq: BIEN 186 or equiv.; or ENME 151 or equiv.
BIEN 212. Biological Mass Transfer 3 sem. hrs.
Development of the theory of mass transfer. Fick’s law and free diffusion. Osmosis, facilitated diffusion, active transport, transport across cell membranes and applications to cell biology and organ physiology. Offered alternate years.
BIEN 221. Biomechanical and Biomaterial Systems Analysis 3 sem. hrs.
Using fundamentals of biomaterials engineering and biocompatibility, this course is designed to analyze the functions that organs serve and to analyze the efficacy and safety of artificial organs systems. Some organs/tissues that will be discussed include the kidneys, liver, skeleton, skin, heart, muscles, eyes, and ears. The suitability of state-of-the-art artificial organ systems, including artificial hearts, orthopaedic prostheses, kidney dialyzers, and cochlear devices to fulfill the functions of the replaced organs/tissues will be critically examined. Prereq: BIEN 170 and BIEN 175.
BIEN 222. Biomedical Engineering Analysis of Trauma 3 sem. hrs.
An engineering analysis of the physiological changes following impact to the head, spinal cord, and limbs, and electrical events and effects on tissues are treated. Offered occasionally.
BIEN 230. Muscoskeletal Biomechanics 1 3 sem. hrs.
Emphasizes the interrelationship of force and motion as related to anatomic structure and function. The student will become acquainted with the forces and motions acting in the skeletal system and the various techniques used to describe them. Current concepts as revealed in the recent scientific and engineering literature will be highlighted. Topics covered include bone mechanics, joint mechanics, gait kinematics, instrumentation and measurement of biomechanical phenomena, and computer modeling of the musculoskeletal system. Offered alternate years. Prereq: ENME 20 or equiv. and ENME 130 or equiv.
BIEN 231. Musculoskeletal Biomechanics 2 3 sem. hrs.
Advanced concepts of kinematics and mechanics as they apply to the fields of biomechanics and rehabilitation. Aspects of gait, bone and joint surgery, and soft tissue surgery will be covered. Detailed study of joint mechanics, implant applications and mobility device function will be performed. Includes advanced analysis and modeling as well as laboratorybased final project. Offered alternate years. Prereq: BIEN 230.
BIEN 232. Applied Finite Element Analysis in Biomechanics 1 3 sem. hrs.
Introduction to finite element analysis as applied to linear, static problems. Application to problems in plane strain, plane stress, and axisymmetry. Development of shape functions and element stiffness matrices. Although primarily structural analysis, will also consider problems in heat transfer and fluid mechanics. Use of user-written and packaged software. Offered fall term, alternate years. Prereq: ENME 130 or equiv.; and Matrix/Linear Algebra or equiv.
BIEN 233. Applied Finite Element Analysis in Biomechanics 2 3 sem. hrs.
Advanced finite element analysis as applied to nonlinear (both material and geometric nonlinearities), dynamic problems. Use of penalty methods and perturbed Lagrangian methods. Use of user-written and packaged software. Critical reviews of finite element analysis in biomechanical research. Offered occasionally. Prereq: BIEN 232; or CEEN 245 or equiv.
BIEN 235. Biomechanics of the Spine 3 sem. hrs.
Analyzes the anatomical and functional relationships among the hard and soft tissue structures of the spine as a function of vertebral column development, aging, disease and trauma. Emphasis will be given to the mechanisms of external and internal load transfer. Imaging (e.g. CT), experimental and finite element methods will be used to study the effects of physiologic/traumatic loading, surgery and spinal disorders. Current advancements in biomechanical/ clinical literature will be discussed. Offered occasionally.
BIEN 237. Neuromotor Control 3 sem. hrs.
Overview of current issues in neuromotor control and movement biomechanics. Special emphasis on the study of normal and impaired human movement. Topics include: muscle mechanics, biomechanics of movement, neural circuitry, strategies for the neural control of movement (including a discussion of adaptation and motor learning) and potential applications of biomedical engineering techniques to the study and improvement of impaired motor function. Offered occasionally. Prereq: BIEN 155 which may be taken concurrently or equiv.; or cons. of instr.
BIEN 240. Biomedical Instrumentation 3 sem. hrs.
Relationships between instruments for physiologic measurement and monitoring with living systems are explored. Physiologic signals, noise, and available sensors and transducers and their characteristics are discussed from time and frequency domain points of view. Systems topics include various new and conventional medical instrumentation. Other topics include clinical and new clinical laboratory instrumentation, instrumentation for research, artificial organs and prostheses. Includes the use of scientific literature, literature searches, design projects, computer projects. Offered alternate years. Prereq: BIEN 180; or BIEN 187; and high level computer language or equiv.
BIEN 241. Microprocessor Based Biomedical Instrumentation 3 sem. hrs.
Discusses the application of microprocessors, microcontrollers, and digital signal processors to biomedical instrumentation. Designed to complement BIEN 240, which covers transducers, sensors, analog signal conditioning, and analog to digital conversion. The emphasis will be on evaluating the memory, power, resolution, cost, and computational requirements of a particular application, and then selecting a type (microprocessor, microcontroller, or digital signal processor) and particular model of processor to satisfy the system requirements. The students will design at least two complete processor based systems. Offered occasionally. Prereq: Knowledge of digital electronics and microprocessors.
BIEN 242. Radio Frequency Applications in Biomedical Engineering 3 sem. hrs.
Radio frequency design and applications for biomedical engineering and medicine. Circuit elements, equivalent circuits, impedance transformations, Smith Chart, two ports, scattering parameters, amplifiers, resonant circuits, mixers, receivers. Applications include telemetry, transcutaneous power transfer, hyperthermia, rf ablation, magnetic resonance imaging; HP-EESOF LIBRA and Ascent CAD are introduced as analysis and design tools. Guest speakers.Written and oral design reports. Offered occasionally. Prereq: Undergraduate background in circuit theory and analog electronics.
BIEN 249. Advanced Topics in Biomedical Instrumentation 3 sem. hrs.
Advanced topics in design and analysis of biomedical instruments, devices and interfaces. Project approach drawing from current literature and current projects of laboratories of affiliated institutions. Topics include bioelectronics, biomechanics, biomaterials, and rehabilitation engineering. Offered occasionally.
BIEN 250. Biomedical Signal Processing 3 sem. hrs.
Introduces students to statistical processing of biomedical data. Topics include: data acquisition, probability and estimation, signal averaging, power spectrum analysis, windowing, digital filters and data compression. Students will complete several computer projects which apply these processing methods to physiologic signals. Offered alternate years. Prereq: MATH 83; and proficiency in C or FORTRAN.
BIEN 251. Advanced Biomedical Signal Processing 3 sem. hrs.
Covers modern methods of Signal Processing encountered in the bio-medical field including parametric modeling, modern spectral estimation, multivariate analysis, adaptive signal processing, decimation/interpolation, and twodimensional signal analysis. There will be several computer projects which apply these modern techniques to physiologic data. Offered occasionally. Prereq: BIEN 250 or equiv.; knowledge of C or FORTRAN.
BIEN 252. Multidimensional Biomedical Time Series Analysis 3 sem. hrs.
Theory and implementation of methods used to collect, model and analyze multidimensional time series encountered in biomedical applications such as functional imaging, electrophysiologic mapping and the study of physiologic control systems. Offered occasionally. Prereq: BIEN 250; proficiency in C or FORTRAN.
BIEN 259. Advanced Topics in Biomedical Computing 3 sem. hrs.
Application of signal processing, information management, modeling and artificial intelligence techniques in biomedical research and clinical environments. Project approach drawing from current literature and data from laboratories of affiliated institutions. Typical projects include analysis of serially recorded neurophysiologic data, development and solution of physiologic models, application of artificial intelligence to ordering of diagnostic terminology. Offered occasionally.
BIEN 265. Mathematics of Medical Imaging 3 sem. hrs.
The course will begin with an overview of the application of linear systems theory to radiographic imaging (pinhole imaging, transmission and emission tomography), and will cover the mathematics of computed tomography including the analytic theory of reconstructing from projections and extensions to emission computed tomography and magnetic resonance imaging. Topics may also include three-dimensional imaging, noise analysis and image quality, and optimization. This course will have an advanced mathematical content. Offered occasionally.
BIEN 268. Rehabilitative Biosystems 3 sem. hrs.
Examines the plastic changes in biological systems that occur in response to targeted stimuli. These processes involve responses by cells to chemical, mechanical, or electrical stimuli (which may be related), which may be influenced or directed using engineering techniques. Examines the homeostasis of physiologic systems and their response to pathologic and rehabilitative stimuli. Examines engineering applications involving the diagnosis and rehabilitation of musculoskeletal, neurologic and cardiopulmonary biosystems in the context of the underlying cellular mechanisms. Prereq: BIEN 180 which may be taken concurrently and PHYS 4.
BIEN 269. Modeling Rehabilitative Biosystems 3 sem. hrs.
Introduces students to large-scale mathematical models of various physiological systems of interest in rehabilitation (e.g., cardiovascular, pulmonary, musculoskeletal, etc.). Mathematical modeling is a widely used tool for testing hypotheses regarding the underlying mechanisms of complex systems such as physiological systems in health, disease and recovery. For each, simulation is used to further our understanding of the adaptive processes of these systems in response to physiological/ pathophysiological stresses and rehabilitative interventions. Prereq: BIEN 152 and BIEN 180.
BIEN 289. Topics in Biomedical Engineering 3 sem. hrs.
Subject matter variable as determined by needs of biomedical graduate students. Students may enroll in the course more than once as the subject matter changes. Possible topics: biostatistics, experimental methods, neuro-anatomy, etc. Offered occasionally.
BIEN 295. Independent Study 1-3 sem. hrs.
Offered every term. Prereq: Cons. of instr. And cons. of dept. ch.
BIEN 297. Department Seminar 0 sem. hrs.
Scholarly presentations on current topics in biomedical engineering and related areas by visiting professors, resident faculty and graduate students. Attendance is required of all full-time graduate students. Offered every term. S/U grade assessment. Mandatory for all full-time BIEN graduate students.
BIEN 299. Master’s Thesis 1-6 sem. hrs.
Offered every term. Prereq: Cons. of instr.
BIEN 300. Human Physiology 8 sem. hrs.
Human physiology describes the normal function of cells and organs systems, laying a foundation for understanding the altered physiologic states of specific disease entities and human organism. Computer-simulated laboratory experiences, animal labs and discussion groups reinforce concepts. Offered at the Medical College of Wisconsin. This course has a variable weekly schedule. (Course generally begins in the first week of January.) For planning purposes, MU students must register by December 15 of the previous year. Prereq: Cons. of dept. ch.; taught at the Medical College of Wisconsin.
BIEN 396. Seminar 0-3 sem. hrs.
Offered occasionally.
BIEN 398. Special Topics in Life Sciences 1-9 sem. hrs.
A graduate-level course in selected areas of the life sciences offered at the Medical College of Wisconsin. May be taken for credit by students enrolled in the Ph.D. degree program in biomedical engineering at Marquette University. No more than three 398 courses may be included in the required minimum course work in the Ph.D. program. The schedule of classes often will be variable and may depend on the course. Prereq: Cons. of dept. ch.
BIEN 399. Doctoral Dissertation 1-12 sem. hrs.
Offered every term.
Math and Science Courses Required by
Undergraduate Biomedical Engineering Students
MATH 80. Calculus 1 4 sem. hrs.
Functions of one variable, limits and continuity. The derivative and the definite integral with applications. Offered every term. MATH 21 or equivalent. Equivalent is three to four years of college preparatory mathematics including topics listed in description of MATH 21.
MATH 81. Calculus 2 4 sem. hrs.
The transcendental functions. Techniques of integration including numerical methods. Elementary differential equations. Infinite sequences and series, Taylor Series. Offered every term. Prereq: MATH 80.
MATH 82. Calculus 3 4 sem. hrs.
Three-dimensional analytic geometry including parametric equations, vectors and vector functions. The differential and integral calculus of functions of several variables. Offered every term. Prereq: MATH 81. Biomedical Engineering Students may take either MATH 082 or 086.
MATH 83. Differential Equations 4 sem. hrs.
Methods and techniques applicable to first order, nth order, and systems of first order differential equations. Eigenvalues, eigenvectors, the Wronskian, Laplace transforms, linearization, and phase portraits. Offered every term. Prereq: MATH 82. Biomedical Engineering Students may take either MATH 083 or 087.
MATH 86. Calculus 3 for Biomedical Engineers 3 sem. hrs.
Three-dimensional analytic geometry. The differential and integral calculus of functions of several variables, with applications to biomedical engineering. Offered fall term. Prereq: MATH 81.
MATH 87. Differential Equations for Biomedical Engineers 3 sem. hrs.
Methods and techniques for solving differential equations and systems of differential equations, with applications to biomedical engineering. Offered spring term. Prereq: MATH 82 or MATH 86.
PHYS 3. General Physics with Introductory Calculus 1 4 sem. hrs.
Survey of classical physics for science majors and engineering majors. Kinematics in one and two dimensions. Newton’s laws of motion and dynamics, including rotation of rigid bodies. Energy concepts in physical systems. Newton’s law of universal gravitation. Applications of these principles to simple harmonic motion, wave motion, and fluids. Thermodynamics. A command of high school algebra, geometry and trigonometry is assumed. Requires the use of introductory calculus. Offered fall term. 3 hrs. lec., 2 hrs. lab., 1 hr. quiz. MATH 80 should be taken concurrently or previously.
PHYS 4. General Physics with Introductory Calculus 2 4 sem. hrs.
A continuation of PHYS 3. A survey of classical electromagnetic theory and optics, with a brief introduction to modern physics. Electricity and magnetism: Coulomb’s law, Gauss’ law, the electric field and the electric potential, DC circuits, Ampere’s law, Faraday’s law, electromagnetic waves. Optics: geometric optics, including lenses and mirrors; physical optics, including interference and diffraction phenomena. Modern physics: the origins of quantum mechanics and models of the atom. Offered spring term. 3 hrs. lec., 2 hrs. lab., 1 hr. quiz. Prereq: MATH 80 and PHYS 3; students may either take MATH 81 concurrently or must have taken MATH 81 previously.
BIOL 1. General Biology 1 3 sem. hrs.
Ecology. Theory of evolution. Taxonomy. Animal diversity. Structures of biological molecules. Cell structure and function. Vertebrate animal anatomy, physiology, and development. Offered fall term. 3 hrs. lec., disc.
BIOL 2. General Biology 2 3 sem. hrs.
Glycolysis and cellular respiration. Photosynthesis. Mitosis and meiosis. Mendelian and molecular genetics. Microbial diversity. Plant form and function. Offered spring term. 3 hrs. lec., disc. Prereq: BIOL 1 and CHEM 1; or cons. of instr.
BIOL 90. Principles of Biological Investigation 3 sem. hrs.
Introduction to selected instrumentation and techniques, including light microscopy, staining, aseptic procedures, and spectrophotometry. Other laboratory studies include: cell structure and function, restriction endonuclease effects on DNA, protein extraction and quantification, bacterial studies, vertebrate anatomy (gross and microscopic) and physiology of cardiovascular and nervous systems. Offered every term. 1 hr. lec., 3 hrs. lab. Prereq: BIOL 1.
CHEM 1. General Chemistry 1 4 sem. hrs.
Introductory college chemistry. Fundamental principles of chemistry including stoichiometry, physical states of matter, energy relationships, periodic table, atomic and molecular structure and solutions. The following mathematical concepts are used in CHEM 1 and CHEM 2: Scientific notation, logarithms, the quadratic equation and proportionality. Offered every term. 3 hrs. lec., 3 hrs. lab., 1 hr. disc.
CHEM 2. General Chemistry 2 4 sem. hrs.
Continuation of CHEM 1. Chemistry of metals and nonmetals, kinetics, chemical equilibrium, aqueous equilibria, free energy relationships, electrochemistry, nuclear chemistry, organic chemistry, and chemistry of the transition metals. Qualitative analysis included as part of the laboratory work. Offered every term. 3 hrs. lec., 3 hrs. lab., 1 hr. disc. Prereq: CHEM 1.
CHEM 23. Organic Chemistry 1 4 sem. hrs.
Modern theories of bonding, stereochemistry, synthesis and reaction mechanism. The chemistry of aliphatic hydrocarbons and their functional group derivatives. Laboratory: basic organic manipulations such as distillation, recrystallization, including simple synthesis. Offered every term. 3 hrs. lec., 4 hrs. lab. Prereq: CHEM 2 or CHEM 4. (Required by BIOM and BIOE majors, constrained electrive for BIOC majors)
Additional Engineering Courses Required by
Undergraduate Biomedical Engineering Students
GEEN 3. Engineering Orientation 0 sem. hrs.
No credit. A one-hour-per-week series of lectures, discussions and engineering speakers to assist beginning sophomores to define more clearly their professional goals by acquainting them with diversified career options available to engineers. Topics include: engineering career exploration and development; cooperative education and internships; and job search, resume writing and interviewing techniques. All sophomores and transfer students are required to attend.
ENME 10. Statics 3 sem. hrs.
Fundamentals of forces and force systems. Application to particles and bodies in equilibrium. Emphasizing vector methods in two and three dimensions. Free body diagrams with and without friction. Centroids and moment of inertia. Offered each term. Prereq: MATH 81. same as MEEN 10 or CEEN 10.
ENME 20. Dynamics 3 sem. hrs.
Fundamentals of motion of particles and rigid bodies. Application of Newton’s laws. Principles of position, velocity, and acceleration. Use of work-energy and impulse- momentum methods. Introduction to vibrations. Offered each term. Prereq: CEEN 10, ENME 10, or MEEN 10. Same as MEEN 20 or CEEN 20.
ENME 22. Statics and Dynamics 4 sem. hrs.
Fundamentals of forces, force systems and their application to static and dynamic bodies and systems of particles emphasizing vector methods in two and three dimensions. Equations of equilibrium. Friction, applications of Newton’s laws, energy and momentum methods. Offered each term. Prereq: MATH 81. Same as MEEN 22 or CEEN 22.
ENME 130. Mechanics of Materials 3 sem. hrs.
Fundamentals of stress, strain, axial loading, torsion, bending, transverse loading, stress and strain transformations, beam deflections, energy methods, columns. Offered each term. Prereq: CEEN 10, ENME 10, or MEEN 10. Same as MEEN 130 or CEEN 130.
COEN 20. Software Methodologies 3 sem. hrs.
The first course in software engineering, covering the software life cycle, proper selection of data structures and algorithms, and the availability and choice of programming paradigms for appropriate design and implementation of well-engineered software. An open laboratory and significant programming experiences form an integral part of this course. Offered spring term. Prereq: COEN 51 or COSC 60.
COEN 30. Introduction to Computer Hardware and Software 3 sem. hrs.
Overview of computer hardware: information representation, the control unit, implementation of instruction sets, memories and storage devices, internal bus organization, the arithmetic/ logic unit, the input/output unit, interfacing peripherals. Overview of computer software, operating system components: memory management, input/output, file management, scheduling, resource management. Layered operating system design, programming languages and language translators, application layer design, software tools, and system design and design process. Programming exercises in 80x86 assembly language and in the JAVA programming language. Offered fall term. Prereq: COEN 51 or COSC 60.
COEN 51. Introduction to Computer Programming 3 sem. hrs.
Students will be introduced to computer programming with an emphasis on object-oriented programming (OOP) and OOP design methodologies. The students will learn about typical programming constructs including data types, data structures, control structures, data input and output techniques as well as several algorithms used for solving engineering problems. In addition, students will learn to use modern programming tools in an integrated development environment by focusing on developing software solutions to significant engineering problems.
COEN 120. Data Structures for Engineers 3 sem. hrs.
Data structures and their applications. Includes the study of such data structures as lists, stacks, queues, and trees and their related algorithms. Prereq: Knowledge of the JAVA programming language; COSC 60. Cross-listed with COSC 154.
COEN 171. Computer Hardware 3 sem. hrs.
Overview of computer system design. Cost and performance specification. Design of arithmetic and logic units. Fundamentals of central processor architecture and a comparative study of computer instruction set architectures. Detailed study of microprocessors, including instruction, execution timing and other timing considerations. Discussions of memory and I/O devices, including the interfaces to the CPU and I/O transfer techniques. Study of common bus standards. COEN design elective in the area of hardware engineering. Design elective for Electrical and Electronics major. Offered spring term. Prereq: COEN 30 with minimum grade of C and EECE 112 with minimum grade of C; or COSC 65 or COSC 148 with minimum grade of C and EECE 112 with minimum grade of C .
#COEN 183. Operating Systems and Networking 3 sem. hrs.
Introduces the fundamental concepts of operating systems together with the basics of networking and communications including: memory management, scheduling, concurrent processing, device management, file systems, networking, security, and system performance. Examples are drawn from legacy and modern operating systems. Prereq: COEN 120, COSC 66, or COSC 154.
EECE 10. Electronic Devices and Applications 3 sem. hrs.
Electronic components are discussed including semiconducting diodes, bipolar junction transistors, field effect transistors, etc. These devices will be analyzed from their terminal characteristics and their behavior in representative electronic circuits. Applications for devices include simple power supply analysis and design, class A amplifier analysis including transistor biasing and stability analysis, simple digital logic gates, etc. Offered spring term. Prereq: EECE 11 with minimum grade of C.
EECE 11. Electric Circuits 1 3 sem. hrs.
Kirchhoff’s laws. Mesh, nodal, general nodal and loop analysis of resistive circuits. Linearity and superposition. Source transformations. Thevenin’s and Norton’s theorems. Natural and forced response of transient circuits of first and second order. Computer analysis and design of linear circuits. Offered fall term. Prereq: MATH 81, which may be taken concurrently.
EECE 12. Electric Circuits 2 3 sem. hrs. Sinusoidal steady-state response. Frequency response. Average power and rms values. Complex power. Polyphase circuits. Complex frequency and frequency response. Magnetically coupled circuits. Two-port networks. Laplace transform theory and applications. Computer analysis and design of linear circuits. Offered spring term. Prereq: EECE 11 with minimum grade of C.
EECE 41. Circuits Laboratory 1 1 sem. hr.
Introduction to circuit design, construction, and test. The basics of circuit construction techniques and electronic test measurement skills are covered. Circuit components such as resistors, inductors, capacitors and op-amps are used. Emphasis placed on DC and transient response of circuits. 1 hr. lec., 2 hrs. lab. EECE 11 must be taken concurrently.
EECE 42. Circuits Laboratory 2 1 sem. hr.
Circuit design, construction, and test skills are expanded to include diode circuits and transistor amplifiers as well as passive and active filters. Emphasis placed on DC, AC and transient response of circuits containing passive and active devices. 1 hr. lec., 2 hrs. lab. Prereq: EECE 10, which may be taken concurrently, EECE 11 with minimum grade of C, EECE 12, which may be taken concurrently, and EECE 41 with minimum grade of C.
EECE 111. Analog Electronics 4 sem. hrs.
Analysis and design of analog electronic circuits. Low and high frequency models for both bipolar and field effect transistors. Design features and operating characteristics of integrated linear circuits with emphasis on operational amplifiers and op-amp circuits. Offered spring term. Prereq: EECE 10 with minimum grade of C and EECE 12 with minimum grade of C.
EECE 112. Digital Electronics 4 sem. hrs.
Introduces students to the basic principles of digital circuit analysis and design. Topics covered include: Boolean Algebra, number systems, basic logic gates, standard combinational circuits, combinational design, timing diagrams, flip-flops, sequential design, standard sequential circuits and programmable logic devices. Offered fall term. Prereq: Jr. stndg.
EECE 113. Linear Systems Analysis 4 sem. hrs.
Mathematical models of continuous-time and discrete-time signals and systems are studied in this course. The time domain viewpoint is developed for linear time invariant systemsusing the impulse response and convolution integral. The frequency domain viewpoint is also explored through the Fourier Series and Fourier Transform. Basic filtering concepts including simple design problems are covered. Application of the Laplace transform to block diagrams, linear feedback, and stability including Bode plots are discussed. The sampling theorem, the Z-Transform, and the Discrete Fourier Transform are introduced. Examples of electrical, mechanical, and biomedical signals and systems are used extensively throughout the course. Prereq: EECE 12 with minimum grade of C and MATH 83; or EECE 100 with minimum grade of C and MATH 83; or BIEN 100 with minimum grade of C and MATH 83; or EECE 109 with minimum grade of C and MATH 83.
EECE 143. Digital Electronics Laboratory 2 sem. hrs.
Gaining experience in the design, assembly, testing, and trouble-shooting of digital electronic circuits. Experiments encompass a wide range of topics such as: basic logic gates, integrated circuit specifications, Boolean algebra implementations, standard combinational circuits, sequential circuit design, standard sequential circuits, programmable logic devices, digital interfacing, and microprocessors. 7400 series ICs, PALs, PROMs, and microprocessor devices are used. Offered both terms. 1 hr. lec., 3 hrs. lab. Prereq: COEN 30, which may be taken concurrently, EECE 41 (or equiv.) with minimum grade of C, and EECE 112 with minimum grade of C; or BIEN 185, which may be taken concurrently, EECE 41 (or equiv.) with minimum grade of C, and EECE 112 with minimum grade of C.
MEEN 60. Materials Science 3 sem. hrs.
Atomic structure of matter, types of bonding, crystallography, role of imperfections, and ionic diffusion. Electric, magnetic, dielectric, and semiconducting properties. Mechanical properties, corrosion, and phase diagrams. Offered every term. Prereq: CHEM 1.
MEEN 104. Thermodynamics 1 3 sem. hrs.
Elementary principles of equilibrium thermodynamics of pure and mixed substances, including applications to systems and processes. Relationships between heat and work, the first law of thermodynamics, are applied to either open or closed systems, operating at either steady or unsteady conditions. Second law of thermodynamics is applied to assessing the efficiency of devices and systems. Offered every term. Prereq: MATH 81 and PHYS 3.
MEEN 128. Dynamics of Mechanical Systems 3 sem. hrs.
Analytical and computational analysis of the kinematics and kinetics of planar multi-body mechanical systems. Vibration analysis of single degree of freedom systems. Engineering applications including dynamic balancing, vibration absorption and vibration isolation. Offered fall term. Prereq: CEEN 20 and MATH 83; or ENME 20 and MATH 83; or MATH 83 and MEEN 20.
MEEN 141. Computer-Aided Engineering 3 sem. hrs.
Numerical algorithms (math analysis, optimization, function approximation) for analysis and preliminary design of engineering systems. Development and use of MATLAB functions. Finite element software for solid modeling and analysis of elastic systems. Offered fall term. 3 hrs. lec., 1 hr. lab. Prereq: ENME 130 and MEEN 128, or CEEN 130 and MEEN 128, or MEEN 128 and MEEN 130.
MEEN 160. Materials Selection in Mechanical Design 3 sem. hrs.
Design methodology and the criteria for the selection of materials from the four classes of materials (metals, plastics, ceramics and composites) are discussed. Criteria include processing requirements, mechanical properties, and environmental resistance. A rationale for selecting materials based on materials selection charts is presented. The process-structureproperty relationship for ferrous and non-ferrous alloys, plastics, ceramics and composites is presented from the point of view of understanding selection criteria. Considerations of cost and availability are also taken into consideration. Offered fall term. 3 hrs. lec., 3 hrs. lab. Prereq: MEEN 60.
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